Respiratory and immunological reactions among Shiitake (Lentinus edodes) mushroom workers. It can also be made into soup or tea. 1998;18(11):665-667. Joe King began writing fitness and nutrition articles in 2001 for the "Journal of Hyperplasia Research" and Champion Nutrition. Cutis. 2003;44(2):155-157. Nihon Kokyuki.Gakkai Zasshi 2000;38(12):908-913. View abstract. [A comparative clinical trial with tegafur plus lentinan treatment at two different doses in advanced cancer]. 2020 Int.J.Immunopharmacol. 2000;20(6C):4707-4711. Br J Gen Pract. Reishi mushrooms can also help balance hormone levels and keep blood sugar in check. View abstract. Corazza M, Zauli S, Ricci M, et al. An individual might also be in a state of hallucination. Shozushima M, Ohata K, Nonaka K, Matsuhashi N. Shiitake mushroom-induced ileus managed using double-balloon enteroscopy. Lentinan is used by … Mashiko, H., Satoh, J., Hatayama, H., and Kitamura, H. [A case of advanced gastric cancer with liver metastasis completely responding to a combined immunochemotherapy with UFT, mitomycin C and lentinan]. What are the side effects of shiitake mushrooms? This happens because your … Turkey tail mushrooms are full of beta-glucan polysaccharides. deVere White RW, Hackman RM, Soares SE, et al. C haga is quite safe on side effects. Shiitake mushroom is LIKELY SAFE when consumed by mouth in food amounts, but it seems POSSIBLY UNSAFE to take by mouth in medicinal amounts. Two cases of small bowel obstruction due to a shiitake mushroom. Zhang, P. and Cheung, P. C. Evaluation of sulfated Lentinus edodes alpha-(1-->3)-D-glucan as a potential antitumor agent. View abstract. Urology 2002;60:640-4.. View abstract. All rights reserved. Nguyen AH, Gonzaga MI, Lim VM, Adler MJ, Mitkov MV, Cappel MA. View abstract. J Eur Acad Dermatol Venereol. View abstract. Gan To Kagaku Ryoho 1988;15(4 Pt 2-1):827-833. II. View abstract. King holds a Bachelor of Science in kinesiology from California State University, Hayward, and a Master of Science in exercise physiology from California State University, East Bay. Gan To Kagaku Ryoho 1986;13(4 Pt 2):1270-1276. J Gastroenterol 1998;33:562-5. 1995;11:111-128. Although rare, shiitake mushroom intake has been associated with dermatitis and photosensitivity, according to an article published in the journal of "Dermatology." View abstract. Shimizu, Y., Hasumi, K., Chen, J. T., Hirai, Y., Nakayama, K., Teshima, H., Hamada, T., Fujimoto, I., Yamauchi, K., and Masubuchi, K. [Successful treatment of a patient with recurrent ovarian cancer by lentinan combined with intraarterial 5FU]. . Shiitake dermatitis recorded by French Poison Control Centers - new case series with clinical observations. View abstract. Agric.Biol Chem 1990;54(2):479-487. 1. Nishihira T, Akimoto M, Mori S. [Anti-cancer effects of BRMs associated with nutrition in cancer patients]. Tani, M., Tanimura, H., Yamaue, H., Tsunoda, T., Iwahashi, M., Noguchi, K., Tamai, M., Hotta, T., and Mizobata, S. Augmentation of lymphokine-activated killer cell activity by lentinan. View abstract. Kunitomo, K., Kawahito, M., Miura, M., and Komi, N. [Combination therapy with lentinan, mitomycin c, 5-fluorouracil and radiation--a case of long-term survival of pancreas cancer after palliative surgery]. Shiitake dermatitis - now also in Poland. Gordon M, Bihari B, Goosby E, et al. Lippert, U., Martin, V., Schwertfeger, C., Junghans, V., Ellinghaus, B., and Fuchs, T. Shiitake dermatitis. (Berl) 1988;177(5):235-244. View abstract. Other digestive side effects include upset stomach, nausea, persistent stomach cramps, and vomiting. Prikl.Biokhim.Mikrobiol. Nippon Geka Gakkai Zasshi 1991;92(1):5-11. An Bras Dermatol. Flagellate shiitake mushroom dermatitis. Shiitake is used as an anti-cancer drug in Japan and sanctioned for this purpose by their FDA.It has many health benefits, such as it’s ability to lower blood pressure and reduce cholesterol. Cancer Immunol.Immunother. 2005;5(5):811-820. ; 1998, "Dermatology"; Flagellate Mushroom (Shiitake) Dermatitis and Photosensitivity; K. Hanada and I. Hashimoto; 1998, PARTNER & LICENSEE OF THE LIVESTRONG FOUNDATION. View abstract. Hardening of the arteries (atherosclerosis). 2013 May-Jun;88(3):417-9. Loo HV, Oon HH. Gan To Kagaku Ryoho 1985;12(2):366-378. Side Effects & Safety It can cause stomach discomfort, blood abnormalities, and skin swelling (inflammation). View abstract. Early research suggests that shiitake mushroom does not prevent prostate cancer from becoming worse. Alder, oak, beech, and poplar are a few others that these may infect. Miyakoshi, H., Aoki, T., and Mizukoshi, M. Acting mechanisms of Lentinan in human--II. View abstract. Individual diversity of IL-6 generation by human monocytes with lentinan administration. 2003;39(1):69-73. [Antimicrobial action of Lentinus edodes juice on human microflora]. Hinyokika Kiyo 1994;40:119-23. But, anything that is proven to be beneficial is also limited to some extent and the same principle applies to mushrooms as well. Nowadays mushrooms are known as superfoods because of high nutrients and protein content. 2014 Oct;27(5):871-4. Poppe LM, Anders D, Kneitz H, Bröcker EB, Benoit S. Flagellate dermatitis caused by shiitake mushrooms. [A case of long survival with UFT and lentinan treatment in a patient with peritoneal metastasis of gastric carcinoma]. View abstract. Shiitake mushrooms are generally safe for consumption though they can cause minor reactions in certain individuals. View abstract. Gan To Kagaku Ryoho 1994;21:2323-5. View abstract. The allergies caused by shiitake mushroom can affect your lungs, throat, nose, skin. Cutis. A placebo-controlled trial of the immune modulator, lentinan, in HIV-positive patients: a phase I/II trial. Baran W, Batycka-Baran A, Maj J, Szepietowski JC. Gan To Kagaku Ryoho,1988;15:1615-20. Gan To Kagaku Ryoho 1988;15(2):319-324. As a dietary supplement, take 1,000 mg (scant 1/2 tsp) of shiitake extract powder once or twice daily, or as directed by a physician. Pravettoni V, Primavesi L, Piantanida M. Shiitake mushroom (Lentinus edodes): a poorly known allergen in Western countries responsible for severe work-related asthma. These effects are typically associated with a large intake of shiitake mushrooms in a single serving and is most likely related to your body's inability to process the contents of the mushroom all at once. All information will be used in a manner consistent with the WebMD, Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Coronavirus in Context: Interviews With Experts, Sign Up to Receive Our Free Coroanvirus Newsletter. [10] Eosinophilic oesophagitis developed after intake of shiitake mushroom … J Biomed Biotechnol. Contact Dermatitis 1992;26:228-33. Clin.Exp.Allergy 1990;20(1):13-19. Gan To Kagaku Ryoho 1990;17(8 Pt 2):1588-1591. 1997;61(11):1909-1912. There are some side effects that are associated with shiitake mushrooms, including gastrointestinal distress, a worsening of autoimmune disease, sensitivity to the sun and allergic reactions. Clin Toxicol (Phila). View abstract. [Treatment for peritoneal dissemination of gastric cancer by intraperitoneal administration of CDDP through Infuse-a-Port]. Privacy Policy Yin, G., Yu, J., and Li, D. [Immune modulatory and therapeutic effect of lentinan on condyloma acuminatum]. 1999;13(2):133-137. Int.J.Immunopharmacol. Matsui S, Nakazawa T, Umegae Y, Mori M. Hypersensitivity pneumonitis induced by Shiitake mushroom spores. Yamamoto, S., Takatori, K., Ohmoto, K., Ideguchi, S., Yamamoto, R., Ohumi, T., Hino, K., and Hirano, Y. (check all that apply), What factors are most important to you? 2015 Mar-Apr;90(2):276-8. 2015 Apr;40(3):332-3. Dermatol Reports. 2015 May;95(5):E11-2. View abstract. Nippon Gan Chiryo Gakkai Shi 10-20-1982;17(7):1895-1901. 2009 Dec;34(8):e910-3. The first signs appear 24 hours upon consumption and may be worsened by sun exposure. Alternative and Complementary Therapies 1998;4(1):53-59. Nippon Geka Hokan 5-1-1989;58(3):310-319. It is a whole food. View abstract. Phytother.Res. LIVESTRONG is a registered trademark of the LIVESTRONG Foundation. Li, J. F., Guo, J. W., and Huang, X. F. [Study on the enhancing effect of polyporus polysaccharide, mycobacterium polysaccharide and lentinan on lymphokine-activated killer cell activity in vitro]. Clin Exp Dermatol. View abstract. Ning, J., Zhang, W., Yi, Y., Yang, G., Wu, Z., Yi, J., and Kong, F. Synthesis of beta-(1-->6)-branched beta-(1-->3) glucohexaose and its analogues containing an alpha-(1-->3) linked bond with antitumor activity. These mushrooms are a form of fungus and overconsumption can cause some serious side effects. Shiitake dermatitis: a report of 3 cases and review of the literature. J Intern Med 1997;241:85-8. Wakui, A., Kasai, M., Konno, K., Abe, R., Kanamaru, R., Takahashi, K., Nakai, Y., Yoshida, Y., Koie, H., Masuda, H., and . Side Effects Of Shiitake Mushrooms Shiitake mushroom are safe to consume, however in rare cases it may cause side effects like skin rash or stomach upset. Gordon M, Guralnik M, Kaneko Y, et al. J Med 1998;29:305-30. Suzuki, H., Iiyama, K., Yoshida, O., Yamazaki, S., Yamamoto, N., and Toda, S. Structural characterization of the immunoactive and antiviral water-solubilized lignin in an extract of the culture medium of Lentinus edodes mycelia (LEM). Yakugaku Zasshi 1974;94(6):708-716. View abstract. Enhanced induction of lymphokine-activated killer activity after lentinan administration in patients with gastric carcinoma. Ishibashi, H., Hirakawa, K., Nakajima, H., Ioka, J., Shirono, K., Tanabe, S., Ochiai, K., Tomita, K., and Kitagawa, Y. View abstract. 2012 Aug;50(6):654-7. Int.J.Antimicrob.Agents 2001;17(1):71-74. Cancer Detect Prev Suppl 1987;1:333-49. Dermatol 1998;197:255-7. Cancer Res 1984;44(11):5132-5137. Nimura, H., Mitsumori, N., Takahashi, N., Kashimura, H., Takayama, S., Kashiwagi, H., and Yanaga, K. [S-1 combined with lentinan in patients with unresectable or recurrent gastric cancer]. Fujiwara, K., Sato, T., Yonei, T., Genba, K., Nogami, N., and Yamadori, I. View abstract. [Randomized study of lentinan on patients with advanced gastric and colorectal cancer. Levy AM, Kita H, Phillips SF, et al. Int.J.Immunopharmacol. It might also cause an increased sensitivity to the sun, allergic skin reactions, and breathing problems. Nippon Gan Chiryo Gakkai Shi 3-20-1989;24(3):647-651. Allergy. Tohoku Lentinan Study Group]. Keep in mind that natural products are not always necessarily safe and dosages can be important. Horiguchi, M., Saito, A., and Sonoda, H. [A gastric cancer showing marked improvement (stage IV) with lentinan immunotherapy and 5-FU, MMC-chemotherapy]. Information from this source is evidence-based and objective, and without commercial influence. View abstract. The American Cancer Society notes that shiitake mushrooms are generally considered safe, although they may cause digestive distress, including bloating and diarrhea. Tanabe, H., Imai, N., and Takechi, K. [Studies on usefulness of postoperative adjuvant chemotherapy with lentinan in patients with gastrointestinal cancer]. A number of studies have shown that turkey tail mushrooms have immune boosting properties. Int J Occup Med Environ Health. 2003;148(1):178-179. Immunopharmacology 1998;40(3):187-198. Precautions and Side Effects: Shiitake mushroom has been used safely by millions of people of all ages throughout the world for centuries. Gan To Kagaku Ryoho 1987;14:516-22. Ricar J, Pizinger K, Cetkovska P. Shiitake dermatitis: a distinctive clinical entity. American Cancer Society; Shiitake Mushroom, "Journal of Allergy and Clinical Immunology"; Eosinophilia and Gastrointestinal Symptoms After Ingestion of Shiitake Mushrooms; A.M. Levy et al. View abstract. Med.Microbiol.Immunol. This information is meant to supplement, not replace advice from your doctor or healthcare provider and is not meant to cover all possible uses, precautions, interactions or adverse effects. Absent Minded. Yamamoto, Y., Shirono, H., Kono, K., and Ohashi, Y. Immunopotentiating activity of the water-soluble lignin rich fraction prepared from LEM--the extract of the solid culture medium of Lentinus edodes mycelia. 2002;66(5):1052-1056. View abstract. Turkey Tail. Akimoto, M., Nishihira, T., and Mori, S. [Modulation of anticancer effects of immunochemotherapeutic agents in various nutritional environments]. Tooth plaque. 19th Annual San Antonio Breast Cancer Symposium, (San Antonio, Texas) 1996;265. 2014 Jun;31(3):187-90. How to … Gan To Kagaku Ryoho 1990;17(1):137-140. © 2005 - 2019 WebMD LLC. Takeshita, M., Kobori, T., Sudo, E., Miyamoto, Y., and Izuo, M. [Preoperative immunochemotherapy for gastric cancer patients--immunomodulating effect of levamisole and lentinan on cell-mediated immunity and regional lymph node]. Shiitake mushroom consumption can cause skin lesions to appear, a condition known as shiitake dermatitis in Japan. Life Sci 11-14-2003;73(26):3363-3374. 1993;15(6):751-756. View abstract. Shiitake mushrooms are a type of edible fungus that is native to Asia and can be consumed raw, cooked, or in nutritional supplement form as a powdered extract of the mushroom's contents. Intern Med 1992;31:1204-6. Peter, G., Karoly, V., Imre, B., Janos, F., and Kaneko, Y. These melanin-rich black mushrooms look like burnt charcoal engulfing a rusty inside. Int.J.Immunopharmacol. In vivo effect on NK activity, MLR induced killer activity and PHA induced blastic response of lymphocytes in cancer patients]. View abstract. Sia, G. M. and Candlish, J. K. Effects of shiitake (Lentinus edodes) extract on human neutrophils and the U937 monocytic cell line. View abstract. Int J Dermatol. Liu, M., Li, J., Kong, F., Lin, J., and Gao, Y. View abstract. Il-6 generation by human monocytes with peritoneal metastasis of gastric, colorectal, and,... 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